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CG3597 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33420, updated on 10-May-2024

Summary

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Official Symbol
CG3597provided by FlyBase
Primary source
FLYBASE:FBgn0031417
Locus tag
Dmel_CG3597
See related
AllianceGenome:FB:FBgn0031417
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BVRA; Dmel\CG3597
Summary
Predicted to enable oxidoreductase activity. Is expressed in adult head; head mesoderm; and plasmatocyte primordium. Orthologous to human DHDH (dihydrodiol dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG3597 in Genome Data Viewer
Location:
22E1-22E1; 2-6 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2370152..2371524, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2370152..2371524, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Rab5 Neighboring gene AXIN1 up-regulated 1 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44982 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The expression pattern of the Drosophila vesicular glutamate transporter: a marker protein for motoneurons and glutamatergic centers in the brain. Mahr A, et al. Gene Expr Patterns, 2006 Mar. PMID 16378756
  2. Chronic low-dose γ-irradiation of Drosophila melanogaster larvae induces gene expression changes and enhances locomotive behavior. Kim CS, et al. J Radiat Res, 2015 May. PMID 25792464, Free PMC Article
  3. The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. King-Jones K, et al. Cell Metab, 2006 Jul. PMID 16814731
  4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables D-xylose 1-dehydrogenase (NADP+) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-xylose catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3597-PA
CG3597-PB
NP_001259930.1
NP_608674.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2370152..2371524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134830.2 → NP_608674.1  uncharacterized protein Dmel_CG3597, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608674.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX02, Q9VQB3
    Related
    FBpp0077469
    Conserved Domains (3) summary
    COG0673
    Location:7 → 330
    MviM; Predicted dehydrogenase [General function prediction only]
    pfam01408
    Location:7 → 128
    GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
    cl21649
    Location:140 → 226
    GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain

  2. NM_001273001.1 → NP_001259930.1  uncharacterized protein Dmel_CG3597, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259930.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PE54, Q8SX02
    Conserved Domains (3) summary
    COG0673
    Location:7 → 332
    MviM; Predicted dehydrogenase [General function prediction only]
    pfam01408
    Location:7 → 127
    GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
    cl21649
    Location:142 → 228
    GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PE54 M9PE54
Q8SX02 Q8SX02
Q9VQB3 Q9VQB3

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