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col1a1a - collagen, type I, alpha 1a

Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; fin development; and fin regeneration. Located in cytoplasm. Is expressed in several structures, including head; integument; myotome; pectoral fin; and vertebra. Used to study osteogenesis imperfecta and osteogenesis imperfecta type 3. Human ortholog(s) of this gene implicated in several diseases, including Ehlers-Danlos syndrome arthrochalasia type 1; aggressive periodontitis; bone disease (multiple); cutaneous leishmaniasis; and dentinogenesis imperfecta. Orthologous to human COL1A1 (collagen type I alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa