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LINC02774 long intergenic non-protein coding RNA 2774 [ Homo sapiens (human) ]

Gene ID: 339529, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02774provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2774provided by HGNC
Primary source
HGNC:HGNC:27923
See related
Ensembl:ENSG00000226828 AllianceGenome:HGNC:27923
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
1q44
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (243917402..244047317)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (243332936..243463802)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (244080704..244210619)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene AKT serine/threonine kinase 3 Neighboring gene fatty acid binding protein 7 pseudogene 1 Neighboring gene VISTA enhancer hs545 Neighboring gene NANOG hESC enhancer GRCh37_chr1:243903627-243904128 Neighboring gene AKT3 intronic transcript 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:244012454-244012954 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:244087610-244088258 Neighboring gene Sharpr-MPRA regulatory region 14056 Neighboring gene uncharacterized LOC105373258 Neighboring gene uncharacterized LOC124904570 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2831 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2832 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2012 Neighboring gene NANOG hESC enhancer GRCh37_chr1:244215360-244215861 Neighboring gene Sharpr-MPRA regulatory region 3339 Neighboring gene uncharacterized LOC440742 Neighboring gene zinc finger and BTB domain containing 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Genome-wide meta-analysis for severe diabetic retinopathy. Grassi MA, et al. Hum Mol Genet, 2011 Jun 15. PMID 21441570, Free PMC Article
  2. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Del-Aguila JL, et al. Pharmacogenomics J, 2014 Feb. PMID 23400010, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
EBI GWAS Catalog
Genome-wide meta-analysis for severe diabetic retinopathy.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033883.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590483, AL591885, BC046644
    Related
    ENST00000440494.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    243917402..244047317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    243332936..243463802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases