OR52B6 olfactory receptor family 52 subfamily B member 6 [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR52B6provided by HGNC
Official Full Name: olfactory receptor family 52 subfamily B member 6provided by HGNC
Primary source: HGNC:HGNC:15211
See related: Ensembl:ENSG00000187747 AllianceGenome:HGNC:15211
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: OR11-47
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs: all
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Genomic context

Location:: 11p15.4

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	11	NC_000011.10 (5580877..5581884)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	11	NC_060935.1 (5640298..5641305)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	11	NC_000011.9 (5602107..5603114)

Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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General gene information

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Markers

ECD01293 (e-PCR)
- UniSTS:282399

REN98782 (e-PCR)
- UniSTS:423579

REN98783 (e-PCR)
- UniSTS:423580

REN98784 (e-PCR)
- UniSTS:423581

REN98785 (e-PCR)
- UniSTS:423582

REN98786 (e-PCR)
- UniSTS:423583

REN98787 (e-PCR)
- UniSTS:423584

REN98788 (e-PCR)
- UniSTS:423585

REN98789 (e-PCR)
- UniSTS:423586

REN98790 (e-PCR)
- UniSTS:423587

REN98791 (e-PCR)
- UniSTS:423588

REN98792 (e-PCR)
- UniSTS:423589

REN98793 (e-PCR)
- UniSTS:423590

ECD23616 (e-PCR)
- UniSTS:304600

ECD20276 (e-PCR)
- UniSTS:301279

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	TAS Traceable Author Statement more info

General protein information

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Preferred Names: olfactory receptor 52B6

Names: olfactory receptor OR11-47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.