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MS4A10 membrane spanning 4-domains A10 [ Homo sapiens (human) ]

Gene ID: 341116, updated on 26-Nov-2021

Summary

Official Symbol
MS4A10provided by HGNC
Official Full Name
membrane spanning 4-domains A10provided by HGNC
Primary source
HGNC:HGNC:13368
See related
Ensembl:ENSG00000172689 MIM:608403
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MS4A9; CD20L7
Summary
Most MS4A genes, including MS4A10, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]
Expression
Biased expression in small intestine (RPKM 35.3) and duodenum (RPKM 30.3) See more
Orthologs
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Genomic context

See MS4A10 in Genome Data Viewer
Location:
11q12.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (60785332..60801305)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (60552806..60568778)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene membrane spanning 4-domains A18 Neighboring gene membrane spanning 4-domains A15 Neighboring gene uncharacterized LOC105369322 Neighboring gene coiled-coil domain containing 86 Neighboring gene prostaglandin D2 receptor 2 Neighboring gene zona pellucida glycoprotein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16054

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
membrane-spanning 4-domains subfamily A member 10
Names
CD20 antigen-like 7
membrane-spanning 4-domains, subfamily A, member 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_206893.4NP_996776.2  membrane-spanning 4-domains subfamily A member 10

    See identical proteins and their annotated locations for NP_996776.2

    Status: VALIDATED

    Source sequence(s)
    AK122633, AP004243
    Consensus CDS
    CCDS7992.1
    UniProtKB/Swiss-Prot
    Q96PG2
    Related
    ENSP00000311862.1, ENST00000308287.2
    Conserved Domains (1) summary
    pfam04103
    Location:60193
    CD20; CD20-like family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    60785332..60801305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544991.2XP_011543293.1  membrane-spanning 4-domains subfamily A member 10 isoform X2

  2. XM_011544989.1XP_011543291.1  membrane-spanning 4-domains subfamily A member 10 isoform X1

    See identical proteins and their annotated locations for XP_011543291.1

    Conserved Domains (1) summary
    pfam04103
    Location:60193
    CD20; CD20-like family
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