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Yip1d1 Yip1 domain-containing 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34696, updated on 10-May-2024

Summary

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Official Symbol
Yip1d1provided by FlyBase
Official Full Name
Yip1 domain-containing 1provided by FlyBase
Primary source
FLYBASE:FBgn0032465
Locus tag
Dmel_CG12404
See related
AllianceGenome:FB:FBgn0032465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12404; Dmel\CG12404; Yip1
Summary
Involved in positive regulation of synapse pruning and spermatogenesis. Located in cis-Golgi network and endoplasmic reticulum exit site. Is expressed in adult head. Used to study azoospermia. Orthologous to several human genes including YIPF5 (Yip1 domain family member 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Yip1d1 in Genome Data Viewer
Location:
34A4-34A4; 2-47 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12993757..13000635, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12993757..13000635, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Vacuolar H[+] ATPase 68 kDa subunit 2 Neighboring gene Vacuolar H[+] ATPase 68kD subunit 3 Neighboring gene Vacuolar H[+] ATPase 68kD subunit 1 Neighboring gene mechanistic Target of rapamycin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yif1 associates with Yip1 on Golgi and regulates dendrite pruning in sensory neurons during Drosophila metamorphosis. Wang Q, et al. Development, 2018 Jun 13. PMID 29769219
  2. Genome-wide mapping of matrix attachment regions in Drosophila melanogaster. Pathak RU, et al. BMC Genomics, 2014 Nov 25. PMID 25424749, Free PMC Article
  3. Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila. Yu J, et al. Hum Mol Genet, 2015 Mar 1. PMID 25361961
  4. Spatiotemporal regulation of developmental neurite pruning: Molecular and cellular insights from Drosophila models. Furusawa K, et al. Neurosci Res, 2021 Jun. PMID 33309868
  5. Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. Marcogliese PC, et al. Cell Rep, 2022 Mar 15. PMID 35294868, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of synapse pruning IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vesicle fusion with Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cis-Golgi network IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum exit site IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Yip1 domain-containing 1
Names
CG12404-PA
Yip1d1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12993757..13000635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135752.3 → NP_609596.1  Yip1 domain-containing 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609596.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK46
    Related
    FBpp0080011
    Conserved Domains (1) summary
    cl21557
    Location:95 → 264
    Yip1; Yip1 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VK46 Q9VK46

Gene LinkOut

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