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CG9932 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34701, updated on 27-Mar-2024

Summary

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Official Symbol
CG9932provided by FlyBase
Primary source
FLYBASE:FBgn0262160
Locus tag
Dmel_CG9932
See related
AllianceGenome:FB:FBgn0262160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9932; Ef4A; elF-4A; EP2317
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic/larval fat body; organism; and yolk nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
34A4-34A5; 2-47 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13021868..13060140, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13021868..13060140, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ubiquitination factor E4B Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44197 Neighboring gene long non-coding RNA:CR45447

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. González J, et al. PLoS Genet, 2010 Apr 8. PMID 20386746, Free PMC Article
  2. How the insect immune system interacts with an obligate symbiotic bacterium. Douglas AE, et al. Proc Biol Sci, 2011 Feb 7. PMID 20719775, Free PMC Article
  3. Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila. Kang H, et al. Genes Dev, 2015 Jun 1. PMID 26063573, Free PMC Article
  4. Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster. Bogaerts-Márquez M, et al. Mol Ecol, 2021 Feb. PMID 33350518, Free PMC Article
  5. An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. Tseng AS, et al. Genetics, 2002 Sep. PMID 12242236, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9932-PA
CG9932-PC
CG9932-PD
CG9932-PE
elongation factor 4a

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13021868..13060140 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273500.2 → NP_001260429.1  uncharacterized protein Dmel_CG9932, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260429.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCU7
    Conserved Domains (2) summary
    sd00017
    Location:339 → 359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:812 → 832
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001259087.3 → NP_001246016.1  uncharacterized protein Dmel_CG9932, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246016.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NDP0
    Conserved Domains (2) summary
    sd00017
    Location:339 → 359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:816 → 836
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. NM_001273499.1 → NP_001260428.1  uncharacterized protein Dmel_CG9932, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260428.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBA9
    Conserved Domains (2) summary
    sd00017
    Location:339 → 359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:812 → 832
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. NM_135755.3 → NP_609599.1  uncharacterized protein Dmel_CG9932, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609599.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK42
    Related
    FBpp0088895
    Conserved Domains (2) summary
    sd00017
    Location:339 → 359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:816 → 836
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NDP0 M9NDP0
M9PBA9 M9PBA9
M9PCU7 M9PCU7
Q8MSG6 Q8MSG6
Q9VK42 Q9VK42

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