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nht no hitter [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34902, updated on 10-May-2024

Summary

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Official Symbol
nhtprovided by FlyBase
Official Full Name
no hitterprovided by FlyBase
Primary source
FLYBASE:FBgn0041103
Locus tag
Dmel_CG15259
See related
AllianceGenome:FB:FBgn0041103
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS07851.6; CG15259; Dmel\CG15259; dmTAF4b; DS07851.6; dTAF4L; dTAF[[II]]110; Nht; TAF4; Taf4L; TFIID
Summary
Enables protein heterodimerization activity. Involved in regulation of gene expression and spermatogenesis. Located in male germ cell nucleus and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See nht in Genome Data Viewer
Location:
35D1-35D1; 2-51 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15317954..15318901, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15317954..15318901, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43764 Neighboring gene uncharacterized protein Neighboring gene escargot Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. To be or not be (in the LAD): emerging roles of lamin proteins in transcriptional regulation. Nazer E. Biochem Soc Trans, 2022 Apr 29. PMID 35437578, Free PMC Article
  2. Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters. O'Keefe DD, et al. BMC Genomics, 2012 Sep 20. PMID 22992320, Free PMC Article
  3. mgm 1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells. Streit A, et al. Int J Dev Biol, 2002 Jan. PMID 11902678
  4. The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Ryder E, et al. Genetics, 2007 Sep. PMID 17720900, Free PMC Article
  5. Approaches to defining the ancestral eukaryotic protein complexome. Ceulemans H, et al. Bioessays, 2006 Mar. PMID 16479579

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to RNA polymerase II general transcription initiation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
no hitter
Names
CG15259-PB
nht-PB
nohitter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    15317954..15318901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078850.4 → NP_523574.4  no hitter [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523574.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V6W2, Q5UEC5, Q9NK90, Q9VJP5
    Conserved Domains (1) summary
    cd08045
    Location:10 → 238
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5UEC5 Q5UEC5
Q9VJP5 Q9VJP5

Gene LinkOut

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