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ND-B17 NADH dehydrogenase (ubiquinone) B17 subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34925, updated on 8-Apr-2024

Summary

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Official Symbol
ND-B17provided by FlyBase
Official Full Name
NADH dehydrogenase (ubiquinone) B17 subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0001989
Locus tag
Dmel_CG13240
See related
AllianceGenome:FB:FBgn0001989
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GM23292; BG:DS09217.1; CG13240; Dmel\CG13240; dNDUFB6; l(2)35Di; NB7M; NDUFB6
Summary
Predicted to enable NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut; embryonic/larval midgut primordium; and spermatozoon. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
35D4-35D4; 2-51 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15749319..15751078, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15749319..15751078, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cyclin E Neighboring gene long non-coding RNA:CR44974 Neighboring gene antisense RNA:CR44866 Neighboring gene small nuclear RNA U5 at 35D Neighboring gene Mtr4 helicase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Mitochondria-Targeted Plastoquinone-Derivative SkQ1 Promotes Health and Increases Drosophila melanogaster Longevity in Various Environments. Tsybul'ko E, et al. J Gerontol A Biol Sci Med Sci, 2017 Apr 1. PMID 27166099, Free PMC Article
  2. Cropped, Drosophila transcription factor AP-4, controls tracheal terminal branching and cell growth. Wong MM, et al. BMC Dev Biol, 2015 Apr 15. PMID 25888431, Free PMC Article
  3. Genetic analysis of speciation by means of introgression into Drosophila melanogaster. Sawamura K, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706624, Free PMC Article
  4. A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. Cai Y, et al. EMBO J, 2001 Apr 2. PMID 11285234, Free PMC Article
  5. The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster. Hossain KFB, et al. Sci Rep, 2022 Dec 27. PMID 36575244, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IC
Inferred by Curator
more info
 PubMed 
involved_in mitochondrial electron transport, NADH to ubiquinone IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial respiratory chain complex I IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NADH dehydrogenase (ubiquinone) B17 subunit
Names
CG13240-PA
CG13240-PC
NADH ubiquinone oxidoreductase B17
NADH-ubiquinone oxidoreductase B17 subunit
NADH:ubiquinone oxidoreductase B17 subunit
ND-B17-PA
ND-B17-PC
lethal (2) 35Di

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    15749319..15751078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165126.3 → NP_723927.2  NADH dehydrogenase (ubiquinone) B17 subunit, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723927.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IP37, Q9V3W2
    Conserved Domains (1) summary
    pfam09782
    Location:9 → 160
    NDUF_B6; NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit

  2. NM_135921.4 → NP_609765.1  NADH dehydrogenase (ubiquinone) B17 subunit, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609765.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IP37, Q9V3W2
    Related
    FBpp0080329
    Conserved Domains (1) summary
    pfam09782
    Location:9 → 160
    NDUF_B6; NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V3W2 Q9V3W2

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