U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Aldoart1 aldolase 1 A, retrogene 1 [ Mus musculus (house mouse) ]

Gene ID: 353204, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Aldoart1provided by MGI
Official Full Name
aldolase 1 A, retrogene 1provided by MGI
Primary source
MGI:MGI:2447811
See related
Ensembl:ENSMUSG00000059343 AllianceGenome:MGI:2447811
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Aldo1-ps; Aldo1-ps2; Aldoa-ps2; 4921524E03Rik
Summary
Predicted to enable several functions, including fructose binding activity; fructose-bisphosphate aldolase activity; and identical protein binding activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; fructose 1,6-bisphosphate metabolic process; and purine ribonucleotide metabolic process. Located in sperm fibrous sheath. Orthologous to human ALDOA (aldolase, fructose-bisphosphate A). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
4 C3; 4 36.06 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (72768820..72770871, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (72850583..72852634, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10525 Neighboring gene predicted gene 11232 Neighboring gene STARR-seq mESC enhancer starr_10526 Neighboring gene STARR-seq mESC enhancer starr_10527 Neighboring gene STARR-seq mESC enhancer starr_10528 Neighboring gene RIKEN cDNA C630043F03 gene Neighboring gene STARR-positive B cell enhancer ABC_E2695 Neighboring gene transducin-like enhancer of split 1 Neighboring gene STARR-seq mESC enhancer starr_10529 Neighboring gene STARR-seq mESC enhancer starr_10530 Neighboring gene STARR-seq mESC enhancer starr_10531 Neighboring gene STARR-seq mESC enhancer starr_10532 Neighboring gene STARR-seq mESC enhancer starr_10533 Neighboring gene STARR-seq mESC enhancer starr_10534 Neighboring gene predicted gene, 25653 Neighboring gene pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular evolution of Aldolase A pseudogenes in mice: multiple origins, subsequent duplications, and heterogeneity of evolutionary rates. Cortinas MN, et al. Mol Biol Evol, 2001 Sep. PMID 11504845
  2. Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition. Vemuganti SA, et al. Dev Biol, 2007 Sep 1. PMID 17659271
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fructose-bisphosphate aldolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fructose 1,6-bisphosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in sperm fibrous sheath IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
aldolase 1 A retrogene 1
Names
aldolase A retroprotein 1
NP_001186199.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199270.1 → NP_001186199.1  aldolase 1 A retrogene 1

    See identical proteins and their annotated locations for NP_001186199.1

    Status: VALIDATED

    Source sequence(s)
    AL928642
    Consensus CDS
    CCDS57279.1
    UniProtKB/TrEMBL
    A6ZI46, Q9CPQ9
    Related
    ENSMUSP00000077687.5, ENSMUST00000078617.5
    Conserved Domains (1) summary
    pfam00274
    Location:70 → 419
    Glycolytic; Fructose-bisphosphate aldolase class-I

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    72768820..72770871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_181346.2: Suppressed sequence

    Description
    NM_181346.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous