Zip42C.2 Zinc/iron regulated transporter-related protein 42C.2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Zip42C.2provided by FlyBase
Official Full Name: Zinc/iron regulated transporter-related protein 42C.2provided by FlyBase
Primary source: FLYBASE:FBgn0033097
Locus tag: Dmel_CG9430
See related: AllianceGenome:FB:FBgn0033097
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: cg9430; CG9430; Dmel\CG9430; dZip2; dZIP2; dZip42C.2; dZIP42C.2; ZIP42C.2
Summary: Enables zinc ion transmembrane transporter activity. Involved in detoxification of zinc ion and zinc ion import across plasma membrane. Located in apical plasma membrane and basolateral plasma membrane. Orthologous to human SLC39A1 (solute carrier family 39 member 1) and SLC39A3 (solute carrier family 39 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (6718196..6719533, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (2605701..2607038, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables metal ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables zinc ion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion transmembrane transporter activity	IC Inferred by Curator more info	PubMed
enables zinc ion transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in detoxification of zinc ion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in metal ion transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in zinc ion import across plasma membrane	IGI Inferred from Genetic Interaction more info	PubMed
involved_in zinc ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in basolateral plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain