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phf-5 PHD finger-like domain-containing protein 5A [ Caenorhabditis elegans ]

Gene ID: 3564851, updated on 23-Nov-2023

Summary

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Gene symbol
phf-5
Gene description
PHD finger-like domain-containing protein 5A
Primary source
WormBase:WBGene00004016
Locus tag
CELE_Y54F10BM.14
See related
AllianceGenome:WB:WBGene00004016
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mRNA splicing, via spliceosome. Located in cytoplasm and nucleus. Is expressed in body wall musculature; intestine; pharynx; and rectal muscle. Orthologous to human PHF5A (PHD finger protein 5A). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (2343573..2347329)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Insulin/EGF-Receptor L Domain protein Neighboring gene Dual specificity protein phosphatase 19 Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene Gamma-tubulin complex component Neighboring gene Serpentine Receptor, class D (Delta)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans ortholog of human PHF5a shows a muscle-specific expression domain and is essential for C. elegans morphogenetic development. Trappe R, et al. Biochem Biophys Res Commun, 2002 Oct 4. PMID 12359262
  2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PHD finger-like domain-containing protein 5A
NP_001022909.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2343573..2347329
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027738.2 → NP_001022909.1  PHD finger-like domain-containing protein 5A [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022909.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBY6
    Conserved Domains (1) summary
    pfam03660
    Location:2 → 104
    PHF5; PHF5-like protein
Nucleotide Protein
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