Dic3 Dicarboxylate carrier 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Dic3provided by FlyBase
Official Full Name: Dicarboxylate carrier 3provided by FlyBase
Primary source: FLYBASE:FBgn0033248
Locus tag: Dmel_CG11196
See related: AllianceGenome:FB:FBgn0033248
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG11196; Dic3p; Dmel\CG11196
Summary: Enables inorganic phosphate transmembrane transporter activity; sulfate transmembrane transporter activity; and thiosulfate transmembrane transporter activity. Involved in phosphate ion transmembrane transport; sulfate transport; and thiosulfate transport. Located in mitochondrion. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome. Orthologous to human SLC25A10 (solute carrier family 25 member 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (7993798..7994968, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (3881303..3882473, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables antiporter activity	IBA Inferred from Biological aspect of Ancestor more info
NOT enables malate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables oxaloacetate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables succinate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables thiosulfate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables thiosulfate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
NOT involved_in malate transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in oxaloacetate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphate ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphate ion transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in succinate transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sulfate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sulfate transport	IDA Inferred from Direct Assay more info	PubMed
involved_in thiosulfate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in thiosulfate transport	IDA Inferred from Direct Assay more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain