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Sdsl serine dehydratase-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 360816, updated on 6-May-2021

Summary

Official Symbol
Sdslprovided by RGD
Official Full Name
serine dehydratase-likeprovided by RGD
Primary source
RGD:1309192
See related
Ensembl:ENSRNOG00000001391
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sdhl
Expression
Biased expression in Liver (RPKM 26.1), Testes (RPKM 13.6) and 5 other tissues See more
Orthologs
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Genomic context

See Sdsl in Genome Data Viewer
Location:
12q16
Exon count:
9
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (36099693..36109914)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (41636994..41647205)

Chromosome 12 - NC_051347.1Genomic Context describing neighboring genes Neighboring gene phospholipase B domain containing 2 Neighboring gene serine dehydratase Neighboring gene uncharacterized LOC108352452 Neighboring gene LIM homeobox 5 Neighboring gene uncharacterized LOC120095980

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables L-threonine ammonia-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in isoleucine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in threonine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
serine dehydratase-like
Names
L-serine dehydratase-like
NP_001101806.1
XP_038945528.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108336.1NP_001101806.1  serine dehydratase-like

    See identical proteins and their annotated locations for NP_001101806.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473973
    UniProtKB/TrEMBL
    D3ZHV7
    Related
    ENSRNOP00000001882.7, ENSRNOT00000001882.6
    Conserved Domains (1) summary
    cd06448
    Location:17326
    L-Ser-dehyd; Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051347.1 Reference mRatBN7.2 Primary Assembly

    Range
    36099693..36109914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089600.1XP_038945528.1  serine dehydratase-like isoform X1

    Conserved Domains (1) summary
    cl00342
    Location:22276
    Trp-synth-beta_II; Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan ...
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