Suds3 SDS3 homolog, SIN3A corepressor complex component [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Suds3provided by RGD
Official Full Name: SDS3 homolog, SIN3A corepressor complex componentprovided by RGD
Primary source: RGD:1305986
See related: Ensembl:ENSRNOG00000001139 AllianceGenome:RGD:1305986
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305986
Summary: Predicted to enable histone deacetylase binding activity and identical protein binding activity. Predicted to contribute to histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of transcription by RNA polymerase II; and substantia nigra development. Predicted to act upstream of or within blastocyst hatching and negative regulation of transcription, DNA-templated. Predicted to be located in cytosol and nuclear body. Predicted to be part of Sin3 complex. Orthologous to human SUDS3 (SDS3 homolog, SIN3A corepressor complex component). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 167.8), Lung (RPKM 148.7) and 9 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (45137964..45160413)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (39477181..39499633)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (45199012..45221507)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables enzyme binding	ISO Inferred from Sequence Orthology more info
contributes_to histone deacetylase activity	ISO Inferred from Sequence Orthology more info
enables histone deacetylase binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone deacetylase binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blastocyst hatching	ISO Inferred from Sequence Orthology more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in substantia nigra development	ISO Inferred from Sequence Orthology more info	PubMed

Component	Evidence Code	Pubs
part_of Sin3-type complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Sin3-type complex	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nuclear body	IEA Inferred from Electronic Annotation more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

Preferred Names: sin3 histone deacetylase corepressor complex component SDS3

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The following sections contain reference sequences that belong to a specific genome build. Explain