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Ccdc25 coiled-coil domain containing 25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361059, updated on 5-Mar-2024

Summary

Official Symbol
Ccdc25provided by RGD
Official Full Name
coiled-coil domain containing 25provided by RGD
Primary source
RGD:1307689
See related
Ensembl:ENSRNOG00000015939 AllianceGenome:RGD:1307689
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307689
Summary
Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of cell motility. Predicted to be located in endomembrane system. Predicted to be integral component of plasma membrane. Orthologous to human CCDC25 (coiled-coil domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 52.1), Muscle (RPKM 50.1) and 9 other tissues See more
Orthologs
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Genomic context

See Ccdc25 in Genome Data Viewer
Location:
15p12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (44230927..44263317)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (40055368..40087758)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (42522108..42555318)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482136 Neighboring gene PDZ binding kinase Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene NOP53 ribosome biogenesis factor, pseudogene 1 Neighboring gene uncharacterized LOC134482135 Neighboring gene scavenger receptor class A, member 3 Neighboring gene clusterin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of cell motility ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endomembrane system ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108382.1NP_001101852.1  coiled-coil domain-containing protein 25

    See identical proteins and their annotated locations for NP_001101852.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474023
    UniProtKB/TrEMBL
    A6K6K7, D4AAU6
    Related
    ENSRNOP00000021621.5, ENSRNOT00000021621.6
    Conserved Domains (1) summary
    pfam05670
    Location:1112
    DUF814; Domain of unknown function (DUF814)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    44230927..44263317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274429.1XP_063130499.1  coiled-coil domain-containing protein 25 isoform X1