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Ercc6l2 ERCC excision repair 6 like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361197, updated on 22-Aug-2021

Summary

Official Symbol
Ercc6l2provided by RGD
Official Full Name
ERCC excision repair 6 like 2provided by RGD
Primary source
RGD:1561537
See related
Ensembl:ENSRNOG00000019175
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561537
Expression
Biased expression in Adrenal (RPKM 203.3), Thymus (RPKM 197.7) and 9 other tissues See more
Orthologs
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Genomic context

See Ercc6l2 in Genome Data Viewer
Location:
17p14
Exon count:
24
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (1076486..1311281, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (1325654..1421732)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member D2 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene uncharacterized LOC102554174 Neighboring gene similar to ribosomal protein L27a

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to reactive oxygen species ISO
Inferred from Sequence Orthology
more info
 
involved_in interstrand cross-link repair ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
colocalizes_with centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
putative DNA repair and recombination protein RAD26-like; DNA excision repair protein ERCC-6-like 2
Names
excision repair cross-complementation group 6-like 2
excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    1076486..1311281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096261.1XP_038952189.1  DNA excision repair protein ERCC-6-like 2 isoform X4

    Conserved Domains (3) summary
    COG0553
    Location:9649
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd18005
    Location:122369
    DEXHc_ERCC6L2; DEXH-box helicase domain of ERCC6L2
    pfam14773
    Location:11321155
    VIGSSK; Helicase-associated putative binding domain, C-terminal
  2. XM_039096260.1XP_038952188.1  DNA excision repair protein ERCC-6-like 2 isoform X3

    Conserved Domains (3) summary
    COG0553
    Location:9649
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd18005
    Location:122369
    DEXHc_ERCC6L2; DEXH-box helicase domain of ERCC6L2
    pfam14773
    Location:11321155
    VIGSSK; Helicase-associated putative binding domain, C-terminal
  3. XM_006253498.4XP_006253560.2  DNA excision repair protein ERCC-6-like 2 isoform X2

    See identical proteins and their annotated locations for XP_006253560.2

    Related
    ENSRNOP00000025965.5
    Conserved Domains (4) summary
    COG0553
    Location:9649
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd00046
    Location:141301
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00271
    Location:505619
    Helicase_C; Helicase conserved C-terminal domain
    pfam14773
    Location:11041127
    VIGSSK; Helicase-associated putative binding domain, C-terminal
  4. XM_039096259.1XP_038952187.1  DNA excision repair protein ERCC-6-like 2 isoform X1

    Conserved Domains (3) summary
    COG0553
    Location:9649
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd18005
    Location:122369
    DEXHc_ERCC6L2; DEXH-box helicase domain of ERCC6L2
    pfam14773
    Location:11321155
    VIGSSK; Helicase-associated putative binding domain, C-terminal
  5. XM_039096262.1XP_038952190.1  DNA excision repair protein ERCC-6-like 2 isoform X5

    Conserved Domains (2) summary
    cd18793
    Location:1123
    SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
    pfam14773
    Location:625648
    VIGSSK; Helicase-associated putative binding domain, C-terminal
  6. XM_039096263.1XP_038952191.1  DNA excision repair protein ERCC-6-like 2 isoform X6

    Conserved Domains (2) summary
    COG0553
    Location:73466
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cl28899
    Location:41254
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

RNA

  1. XR_005495504.1 RNA Sequence

  2. XR_005495506.1 RNA Sequence

  3. XR_005495505.1 RNA Sequence

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