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Auh AU RNA binding methylglutaconyl-CoA hydratase [ Rattus norvegicus (Norway rat) ]

Gene ID: 361215, updated on 5-Jun-2021

Summary

Official Symbol
Auhprovided by RGD
Official Full Name
AU RNA binding methylglutaconyl-CoA hydrataseprovided by RGD
Primary source
RGD:1306087
See related
Ensembl:ENSRNOG00000011684
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Adrenal (RPKM 239.2), Kidney (RPKM 164.8) and 9 other tissues See more
Orthologs
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Genomic context

See Auh in Genome Data Viewer
Location:
17p14
Exon count:
15
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (12329522..12424896)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (12310178..12405224)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097877 Neighboring gene nuclear factor, interleukin 3 regulated Neighboring gene uncharacterized LOC120097808 Neighboring gene uncharacterized LOC108348512 Neighboring gene 40S ribosomal protein S28-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables enoyl-CoA hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables enoyl-CoA hydratase activity ISO
Inferred from Sequence Orthology
more info
 
enables itaconyl-CoA hydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR binding ISO
Inferred from Sequence Orthology
more info
 
enables methylglutaconyl-CoA hydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in branched-chain amino acid catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
methylglutaconyl-CoA hydratase, mitochondrial
Names
AU RNA binding protein/enoyl-CoA hydratase
AU RNA binding protein/enoyl-coenzyme A hydratase
AU-binding enoyl-CoA hydratase
AU-specific RNA-binding enoyl-CoA hydratase
itaconyl-CoA hydratase
NP_001101877.1
XP_006253736.1
XP_006253737.1
XP_008769721.1
XP_038951780.1
XP_038951781.1
XP_038951782.1
XP_038951783.1
XP_038951784.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108407.1NP_001101877.1  methylglutaconyl-CoA hydratase, mitochondrial

    See identical proteins and their annotated locations for NP_001101877.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473977
    Conserved Domains (1) summary
    cl23717
    Location:3253
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    12329522..12424896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095854.1XP_038951782.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X6

    Conserved Domains (1) summary
    cl23717
    Location:62164
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  2. XM_039095855.1XP_038951783.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X7

    Conserved Domains (1) summary
    cl23717
    Location:62164
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  3. XM_039095856.1XP_038951784.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X8

    Conserved Domains (1) summary
    cl23717
    Location:64184
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  4. XM_039095852.1XP_038951780.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X3

    Conserved Domains (1) summary
    cl23717
    Location:62195
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  5. XM_006253675.3XP_006253737.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X2

    Conserved Domains (1) summary
    cl23717
    Location:62284
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  6. XM_039095853.1XP_038951781.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X5

    Conserved Domains (1) summary
    cl23717
    Location:62195
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  7. XM_006253674.3XP_006253736.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_006253736.1

    UniProtKB/Swiss-Prot
    F1LU71
    Related
    ENSRNOP00000015786.5, ENSRNOT00000015786.7
    Conserved Domains (1) summary
    cl23717
    Location:62315
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  8. XM_008771499.3XP_008769721.1  methylglutaconyl-CoA hydratase, mitochondrial isoform X4

    Conserved Domains (1) summary
    cl23717
    Location:2230
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RNA

  1. XR_005495294.1 RNA Sequence

  2. XR_005495293.1 RNA Sequence

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