U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pusl1 pseudouridine synthase like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362681, updated on 2-May-2024

Summary

Go to the top of the page Help
Official Symbol
Pusl1provided by RGD
Official Full Name
pseudouridine synthase like 1provided by RGD
Primary source
RGD:1559560
See related
Ensembl:ENSRNOG00000022354 AllianceGenome:RGD:1559560
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Predicted to be located in mitochondrion. Orthologous to human PUSL1 (pseudouridine synthase like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 88.9), Lung (RPKM 88.1) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Pusl1 in Genome Data Viewer
Location:
5q36
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (171773284..171782893, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (166497643..166500647, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (173326755..173339934, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene dishevelled segment polarity protein 1 Neighboring gene taste 1 receptor member 3 Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene integrator complex subunit 11 Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Neighboring gene sodium channel epithelial 1 delta subunit

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables pseudouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA pseudouridine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA pseudouridine(38-40) synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tRNA pseudouridine synthase-like 1
Names
pseudouridylate synthase-like 1
NP_001382537.1
NP_001382538.1
XP_063144165.1
XP_063144166.1
XP_063144167.1
XP_063144168.1
XP_063144169.1
XP_063144170.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395608.1 → NP_001382537.1  tRNA pseudouridine synthase-like 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A0G2K730
    Related
    ENSRNOP00000074040.2, ENSRNOT00000078453.2
    Conserved Domains (1) summary
    cd02570
    Location:18 → 284
    PseudoU_synth_EcTruA; Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA

  2. NM_001395609.1 → NP_001382538.1  tRNA pseudouridine synthase-like 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    Conserved Domains (1) summary
    cl00130
    Location:18 → 234
    PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    171773284..171782893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288097.1 → XP_063144167.1  tRNA pseudouridine synthase-like 1 isoform X3

  2. XM_063288096.1 → XP_063144166.1  tRNA pseudouridine synthase-like 1 isoform X2

  3. XM_063288100.1 → XP_063144170.1  tRNA pseudouridine synthase-like 1 isoform X6

  4. XM_063288099.1 → XP_063144169.1  tRNA pseudouridine synthase-like 1 isoform X5

  5. XM_063288095.1 → XP_063144165.1  tRNA pseudouridine synthase-like 1 isoform X1

  6. XM_063288098.1 → XP_063144168.1  tRNA pseudouridine synthase-like 1 isoform X4

RNA

  1. XR_010066443.1 RNA Sequence

  2. XR_010066442.1 RNA Sequence

  3. XR_010066441.1 RNA Sequence

  4. XR_010066444.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001108699.1: Suppressed sequence

    Description
    NM_001108699.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous