U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tmem123 transmembrane protein 123 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363013, updated on 30-Mar-2024

Summary

Official Symbol
Tmem123provided by RGD
Official Full Name
transmembrane protein 123provided by RGD
Primary source
RGD:1305625
See related
Ensembl:ENSRNOG00000010584 AllianceGenome:RGD:1305625
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305625
Summary
Predicted to be involved in oncosis. Predicted to be located in external side of plasma membrane. Predicted to be active in cytoplasmic vesicle. Orthologous to human TMEM123 (transmembrane protein 123). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 999.6), Spleen (RPKM 651.5) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
8q11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (13206907..13237069)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (4922077..4952228)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (5967373..5997387)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556477 Neighboring gene galectin-8 pseudogene Neighboring gene matrix metallopeptidase 7 Neighboring gene baculoviral IAP repeat-containing 2 Neighboring gene baculoviral IAP repeat-containing 3 Neighboring gene RNA guanine-7 methyltransferase activating subunit, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014205.2NP_001014227.1  porimin precursor

    See identical proteins and their annotated locations for NP_001014227.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q5HZB0
    UniProtKB/TrEMBL
    A0A8I6A004
    Related
    ENSRNOP00000014065.6, ENSRNOT00000014065.8
    Conserved Domains (1) summary
    pfam05283
    Location:94174
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    13206907..13237069
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063265682.1XP_063121752.1  porimin isoform X1