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Cnot11 CCR4-NOT transcription complex, subunit 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363221, updated on 5-Mar-2024

Summary

Official Symbol
Cnot11provided by RGD
Official Full Name
CCR4-NOT transcription complex, subunit 11provided by RGD
Primary source
RGD:1560909
See related
Ensembl:ENSRNOG00000023220 AllianceGenome:RGD:1560909
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560909
Summary
Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT11 (CCR4-NOT transcription complex subunit 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 75.1), Spleen (RPKM 51.3) and 9 other tissues See more
Orthologs
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Genomic context

Location:
9q22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (49310624..49320325)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (41814923..41824626)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (46270229..46279928)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 Neighboring gene TBC1 domain family, member 8 Neighboring gene uncharacterized LOC134480362 Neighboring gene small nucleolar RNA SNORD89 Neighboring gene ring finger protein 149, pseudogene 2 Neighboring gene ring finger protein 149

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of CCR4-NOT complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of CCR4-NOT complex ISO
Inferred from Sequence Orthology
more info
 
part_of CCR4-NOT complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CCR4-NOT transcription complex subunit 11
Names
UPF0760 protein C2orf29 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108794.2NP_001102264.1  CCR4-NOT transcription complex subunit 11

    See identical proteins and their annotated locations for NP_001102264.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158750
    UniProtKB/Swiss-Prot
    B0BNA9
    Related
    ENSRNOP00000035943.4, ENSRNOT00000031352.6
    Conserved Domains (1) summary
    pfam10155
    Location:365489
    DUF2363; Uncharacterized conserved protein (DUF2363)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    49310624..49320325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267372.1XP_063123442.1  CCR4-NOT transcription complex subunit 11 isoform X1