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Rpl37a ribosomal protein L37A [ Rattus norvegicus (Norway rat) ]

Gene ID: 363248, updated on 2-May-2024

Summary

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Official Symbol
Rpl37aprovided by RGD
Official Full Name
ribosomal protein L37Aprovided by RGD
Primary source
RGD:2319947
See related
Ensembl:ENSRNOG00000063418 AllianceGenome:RGD:2319947
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables large ribosomal subunit rRNA binding activity. Predicted to be involved in translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL37A (ribosomal protein L37a). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Note: In November, 2008, this locus was recognized to be a probable pseudogene. The defining independent sequences, BC088285.1 and X14069, which align better to Chr9, were assigned to GeneID 363248. [17 Jun 2014]
Expression
Biased expression in Spleen (RPKM 5039.6), Thymus (RPKM 4652.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
9q33
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (81748091..81750174)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (74298843..74300926)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (145071367..145071453, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Neighboring gene uncharacterized LOC120094703 Neighboring gene uncharacterized LOC134480591 Neighboring gene uncharacterized LOC120094849

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The primary structure of rat ribosomal protein L37a. Tanaka T, et al. Eur J Biochem, 1989 Jul 15. PMID 2546769
  2. Carbodiimide-induced protein--RNA crosslinking in mammalian ribosomal subunits. Buisson M, et al. FEBS Lett, 1982 Nov 8. PMID 6759166
  3. Sequence of the amino-terminal region of rat liver ribosomal proteins S4, S6, S8, L6, L7a, L18, L27, L30, L37, L37a, and L39. Wittmann-Liebold B, et al. J Supramol Struct, 1979. PMID 398910
  4. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, et al. J Biol Chem, 1977 Jun 10. PMID 863909
  5. Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Lee NH, et al. Proc Natl Acad Sci U S A, 1995 Aug 29. PMID 7667285, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC109163

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables large ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables large ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL43
Names
60S ribosomal protein L37a
putative 60S ribosomal protein L37a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205318.2 → NP_001192247.2  large ribosomal subunit protein eL43

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    P61515
    Related
    ENSRNOP00000078579.1, ENSRNOT00000098542.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    81748091..81750174
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001100994.1: Suppressed sequence

    Description
    NM_001100994.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.

  2. NM_001108801.1: Suppressed sequence

    Description
    NM_001108801.1: This RefSeq was removed because currently there is support for the transcript.

  3. NR_038113.1: Suppressed sequence

    Description
    NR_038113.1: This RefSeq was removed because it is now thought that this gene encodes a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P61515.2 GenPept UniProtKB/Swiss-Prot:P61515

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.