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Or49a Odorant receptor 49a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36350, updated on 10-May-2024

Summary

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Official Symbol
Or49aprovided by FlyBase
Official Full Name
Odorant receptor 49aprovided by FlyBase
Primary source
FLYBASE:FBgn0033727
Locus tag
Dmel_CG13158
See related
AllianceGenome:FB:FBgn0033727
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
49a; 49A.1; CG13158; Dmel\CG13158; DmOr49a; DOR10; OR49a
Summary
Predicted to enable odorant binding activity and olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell and olfactory behavior. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in larval head segment and olfactory system. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Or49a in Genome Data Viewer
Location:
49A2-49A2; 2-67 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12393483..12394842)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8280988..8282347)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 49Ac Neighboring gene Cuticular protein 49Ad Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 49Ae

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Avoids Parasitoids by Sensing Their Semiochemicals via a Dedicated Olfactory Circuit. Ebrahim SA, et al. PLoS Biol, 2015 Dec. PMID 26674493, Free PMC Article
  2. Olfactory coding: connecting odorant receptor expression and behavior in the Drosophila larva. Stocker RF. Curr Biol, 2006 Jan 10. PMID 16401410
  3. Neuropeptide F signaling regulates parasitoid-specific germline development and egg-laying in Drosophila. Sadanandappa MK, et al. PLoS Genet, 2021 Mar. PMID 33770070, Free PMC Article
  4. Chemical Cues that Guide Female Reproduction in Drosophila melanogaster. Billeter JC, et al. J Chem Ecol, 2018 Sep. PMID 29557077, Free PMC Article
  5. Combinatorial Codes and Labeled Lines: How Insects Use Olfactory Cues to Find and Judge Food, Mates, and Oviposition Sites in Complex Environments. Haverkamp A, et al. Front Physiol, 2018. PMID 29449815, Free PMC Article

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in olfactory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
odorant receptor 49a
Names
CG13158-PA
Or49a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12393483..12394842
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078987.3 → NP_523711.3  odorant receptor 49a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523711.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V6A9
    Related
    FBpp0087029, FBtr0087918
    Conserved Domains (1) summary
    pfam02949
    Location:88 → 384
    7tm_6; 7tm Odorant receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V6A9.3 Q9V6A9

Gene LinkOut

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