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Dera Deoxyribose-phosphate aldolase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36358, updated on 4-Apr-2024

Summary

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Official Symbol
Deraprovided by FlyBase
Official Full Name
Deoxyribose-phosphate aldolaseprovided by FlyBase
Primary source
FLYBASE:FBgn0033735
Locus tag
Dmel_CG8525
See related
AllianceGenome:FB:FBgn0033735
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8525; Dmel\CG8525
Summary
Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process and deoxyribonucleotide catabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including embryonic/larval fat body; embryonic/larval midgut primordium; spermatozoon; trunk mesoderm; and wing disc. Orthologous to human DERA (deoxyribose-phosphate aldolase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Dera in Genome Data Viewer
Location:
49A4-49A4; 2-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12425483..12426975)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8312988..8314480)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Nucleoporin 54kD Neighboring gene uncharacterized protein Neighboring gene Deubiquitinating apoptotic inhibitor Neighboring gene Transmembrane protein 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring of female reproductive behaviors in Drosophila. Nallasivan MP, et al. BMC Biol, 2021 Oct 20. PMID 34666772, Free PMC Article
  2. Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Whitaker R, et al. Aging (Albany NY), 2014 May. PMID 24864304, Free PMC Article
  3. Intestinal response to dietary manganese depletion in Drosophila. Vásquez-Procopio J, et al. Metallomics, 2020 Feb 1. PMID 31799578
  4. Genetic annotation of gain-of-function screens using RNA interference and in situ hybridization of candidate genes in the Drosophila wing. Molnar C, et al. Genetics, 2012 Oct. PMID 22798488, Free PMC Article
  5. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables deoxyribose-phosphate aldolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deoxyribose-phosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in deoxyribonucleotide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in deoxyribonucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Deoxyribose-phosphate aldolase
Names
CG8525-PA
CG8525-PD
Dera-PA
Dera-PD
NP_001286348.1
NP_610781.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12425483..12426975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136937.3 → NP_610781.1  Deoxyribose-phosphate aldolase, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610781.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NPB3, Q7K209
    Related
    FBpp0087038
    Conserved Domains (1) summary
    cd00959
    Location:56 → 302
    DeoC; 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family

  2. NM_001299419.1 → NP_001286348.1  Deoxyribose-phosphate aldolase, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286348.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NPB3, Q7K209
    Conserved Domains (1) summary
    cd00959
    Location:56 → 302
    DeoC; 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K209 Q7K209

Gene LinkOut

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