Plcxd2 phosphatidylinositol-specific phospholipase C, X domain containing 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Plcxd2provided by RGD
Official Full Name: phosphatidylinositol-specific phospholipase C, X domain containing 2provided by RGD
Primary source: RGD:1563504
See related: Ensembl:ENSRNOG00000042289 AllianceGenome:RGD:1563504
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563504
Summary: Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 176.1), Kidney (RPKM 37.0) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (68263626..68315962)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (54800977..54853348)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (57207656..57260001)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BG374132 (e-PCR)
- UniSTS:249670

Tox2 (e-PCR), detects polymorphism
- UniSTS:536679

RH139271 (e-PCR)
- UniSTS:221357

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables phosphoric diester hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: PI-PLC X domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001134481.3 → NP_001127953.1 PI-PLC X domain-containing protein 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000011

UniProtKB/TrEMBL

A6IQX1, D4A4P6

Related

ENSRNOP00000073045.1, ENSRNOT00000085754.2

Conserved Domains (1) summary

cd08616
Location:39 → 329

PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1