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Sfxn1 sideroflexin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364678, updated on 5-Jun-2021

Summary

Official Symbol
Sfxn1provided by RGD
Official Full Name
sideroflexin 1provided by RGD
Primary source
RGD:1308482
See related
Ensembl:ENSRNOG00000018279
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
SLC64A1
Expression
Biased expression in Kidney (RPKM 466.1), Liver (RPKM 145.1) and 7 other tissues See more
Orthologs
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Genomic context

See Sfxn1 in Genome Data Viewer
Location:
17p14
Exon count:
14
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10486250..10522640, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (11046588..11082219, complement)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0-like Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene U2 spliceosomal RNA Neighboring gene dopamine receptor D1 Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-serine transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables D-serine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables D-serine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables L-serine transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables L-serine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-serine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables serine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in D-serine transport IEA
Inferred from Electronic Annotation
more info
 
involved_in D-serine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in D-serine transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in L-serine transport IEA
Inferred from Electronic Annotation
more info
 
involved_in L-serine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-serine transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within iron ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of one-carbon metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of one-carbon metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in serine import into mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in serine import into mitochondrion IEA
Inferred from Electronic Annotation
more info
 
involved_in serine import into mitochondrion ISO
Inferred from Sequence Orthology
more info
 
involved_in serine import into mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in integral component of mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sideroflexin-1
Names
TCC
solute carrier family 64 member 1
tricarboxylate carrier protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012213.1NP_001012213.1  sideroflexin-1

    See identical proteins and their annotated locations for NP_001012213.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078935
    UniProtKB/TrEMBL
    Q6AYS2
    Related
    ENSRNOP00000024707.4, ENSRNOT00000024707.7
    Conserved Domains (1) summary
    pfam03820
    Location:16322
    Mtc; Tricarboxylate carrier

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    10486250..10522640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095969.1XP_038951897.1  sideroflexin-1 isoform X2

    Conserved Domains (1) summary
    pfam03820
    Location:10244
    Mtc; Tricarboxylate carrier
  2. XM_008771502.3XP_008769724.1  sideroflexin-1 isoform X1

    See identical proteins and their annotated locations for XP_008769724.1

    UniProtKB/TrEMBL
    Q6AYS2
    Conserved Domains (1) summary
    pfam03820
    Location:16322
    Mtc; Tricarboxylate carrier
  3. XM_039095968.1XP_038951896.1  sideroflexin-1 isoform X2

    Conserved Domains (1) summary
    pfam03820
    Location:10244
    Mtc; Tricarboxylate carrier

RNA

  1. XR_005495309.1 RNA Sequence

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