Slc26a10 solute carrier family 26, member 10 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc26a10provided by RGD
Official Full Name: solute carrier family 26, member 10provided by RGD
Primary source: RGD:1564851
See related: Ensembl:ENSRNOG00000029465 AllianceGenome:RGD:1564851
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564851
Summary: Predicted to enable anion transmembrane transporter activity. Predicted to be involved in anion transport. Predicted to be active in basolateral plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human SLC26A10 (solute carrier family 26 member 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 123.8), Thymus (RPKM 45.5) and 9 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 7q22

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (64880694..64890340, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (62995165..63005099, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (70458528..70469212, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH126364 (e-PCR)
- UniSTS:163072

RH142023 (e-PCR)
- UniSTS:224014

Slc26a10 (e-PCR), detects polymorphism
- UniSTS:547063

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables bicarbonate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables chloride transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxalate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in bicarbonate transport	IEA Inferred from Electronic Annotation more info
involved_in chloride transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in oxalate transport	IEA Inferred from Electronic Annotation more info
involved_in sulfate transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: solute carrier family 26 member 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001134595.3 → NP_001128067.2 solute carrier family 26 member 10

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

A6HQT1, D3ZXL0

Related

ENSRNOP00000049501.4, ENSRNOT00000052288.6

Conserved Domains (2) summary

cd07042
Location:553 → 661

STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function

TIGR00815
Location:91 → 664

sulP; high affinity sulphate transporter 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086025.1 Reference GRCr8

Range

64880694..64890340 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063264052.1 → XP_063120122.1 solute carrier family 26 member 10 isoform X2
XM_063264053.1 → XP_063120123.1 solute carrier family 26 member 10 isoform X3
XM_063264051.1 → XP_063120121.1 solute carrier family 26 member 10 isoform X1
XM_063264050.1 → XP_063120120.1 solute carrier family 26 member 10 isoform X1
XM_039079687.2 → XP_038935615.1 solute carrier family 26 member 10 isoform X4

Conserved Domains (1) summary

pfam00916
Location:105 → 433

Sulfate_transp; Sulfate permease family