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tun tungus [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36743, updated on 4-Apr-2024

Summary

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Official Symbol
tunprovided by FlyBase
Official Full Name
tungusprovided by FlyBase
Primary source
FLYBASE:FBgn0034046
Locus tag
Dmel_CG8253
See related
AllianceGenome:FB:FBgn0034046
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD38553; CG8253; Dmel\CG8253; Ntaq1
Summary
Predicted to enable protein-N-terminal glutamine amidohydrolase activity. Predicted to be involved in cellular protein modification process. Predicted to be active in cytosol and nucleus. Is expressed in organism. Orthologous to human NTAQ1 (N-terminal glutamine amidase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See tun in Genome Data Viewer
Location:
52C5-52C8; 2-75 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15794000..15855645)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11681505..11743150)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Z band alternatively spliced PDZ-motif protein 52 Neighboring gene uncharacterized protein Neighboring gene Pox neuro Neighboring gene uncharacterized protein Neighboring gene cGAS-like receptor 1 Neighboring gene Glycerophosphate oxidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glutamine-specific N-terminal amidase, a component of the N-end rule pathway. Wang H, et al. Mol Cell, 2009 Jun 26. PMID 19560421, Free PMC Article
  2. The Drosophila Pox neuro gene: control of male courtship behavior and fertility as revealed by a complete dissection of all enhancers. Boll W, et al. Development, 2002 Dec. PMID 12421707
  3. dRTEL1 is essential for the maintenance of Drosophila male germline stem cells. Yang Y, et al. PLoS Genet, 2021 Oct. PMID 34644293, Free PMC Article
  4. Shared visual attention and memory systems in the Drosophila brain. van Swinderen B, et al. PLoS One, 2009 Jun 19. PMID 19543525, Free PMC Article
  5. A high-fat diet impacts memory and gene expression of the head in mated female Drosophila melanogaster. Rivera O, et al. J Comp Physiol B, 2019 Apr. PMID 30810797, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
Inferred from Electronic Annotation
more info
  
enables protein-N-terminal asparagine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-N-terminal glutamine amidohydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-N-terminal glutamine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tungus
Names
CG8253-PA
CG8253-PB
CG8253-PC
CG8253-PD
tun-PA
tun-PB
tun-PC
tun-PD
NP_001246351.1
NP_001246352.1
NP_001286468.1
NP_611061.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    15794000..15855645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299539.1 → NP_001286468.1  tungus, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286468.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7K2Y9
    UniProtKB/TrEMBL
    A0A0B4K882
    Conserved Domains (1) summary
    pfam09764
    Location:15 → 185
    Nt_Gln_amidase; N-terminal glutamine amidase

  2. NM_001259422.2 → NP_001246351.1  tungus, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246351.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7K2Y9
    UniProtKB/TrEMBL
    A0A0B4K882
    Conserved Domains (1) summary
    pfam09764
    Location:15 → 185
    Nt_Gln_amidase; N-terminal glutamine amidase

  3. NM_001259423.2 → NP_001246352.1  tungus, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246352.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7K2Y9
    UniProtKB/TrEMBL
    A0A0B4K882
    Conserved Domains (1) summary
    pfam09764
    Location:15 → 185
    Nt_Gln_amidase; N-terminal glutamine amidase

  4. NM_137217.3 → NP_611061.1  tungus, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611061.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7K2Y9
    UniProtKB/TrEMBL
    A0A0B4K882
    Related
    FBpp0086423
    Conserved Domains (1) summary
    pfam09764
    Location:15 → 185
    Nt_Gln_amidase; N-terminal glutamine amidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K882 A0A0B4K882
Q7K2Y9.1 Q7K2Y9
Q95SZ1 Q95SZ1

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