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hpo-12 Mitochondrial thiamine pyrophosphate carrier [ Caenorhabditis elegans ]

Gene ID: 36804989, updated on 11-Apr-2024

Summary

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Gene symbol
hpo-12
Gene description
Mitochondrial thiamine pyrophosphate carrier
Primary source
WormBase:WBGene00016588
Locus tag
CELE_C42C1.10
See related
AllianceGenome:WB:WBGene00016588
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (12283173..12285122)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein-lysine methyltransferase C42C1.13 Neighboring gene Aminopeptidase ltah-1.1 Neighboring gene PAP2_C domain-containing protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Erlin Neighboring gene Protein kinase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables thiamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in thiamine pyrophosphate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Mitochondrial thiamine pyrophosphate carrier
NP_001379467.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12283173..12285122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392411.1 → NP_001379467.1  Mitochondrial thiamine pyrophosphate carrier [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A3QMB9
    Conserved Domains (1) summary
    pfam00153
    Location:115 → 209
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
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