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egf1 fibropellin I [ Strongylocentrotus purpuratus (purple sea urchin) ]

Gene ID: 373313, updated on 14-Dec-2023

Summary

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Gene symbol
egf1
Gene description
fibropellin I
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Strongylocentrotus purpuratus
Lineage
Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
Also known as
EGF; EGFI; UEGF-1; SpEGF I
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Genomic context

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See egf1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
29
Annotation release Status Assembly Chr Location
102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145599.1 (33242473..33268883, complement)
Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577038.1 (1066301..1091842, complement)

NW_022145599.1Genomic Context describing neighboring genes Neighboring gene adhesion G-protein coupled receptor G2-like Neighboring gene fibropellin-1-like Neighboring gene COP9 signalosome complex subunit 1-like Neighboring gene polymerase delta-interacting protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Avidin-like domain in an epidermal growth factor homolog from a sea urchin. Hunt LT, et al. FASEB J, 1989 Apr. PMID 2784773
  2. Structural analysis of the uEGF gene in the sea urchin strongylocentrotus purpuratus reveals more similarity to vertebrate than to invertebrate genes with EGF-like repeats. Delgadillo-Reynoso MG, et al. J Mol Evol, 1989 Oct. PMID 2514273
  3. Fibropellins, products of an EGF repeat-containing gene, form a unique extracellular matrix structure that surrounds the sea urchin embryo. Bisgrove BW, et al. Dev Biol, 1991 Jul. PMID 2060714
  4. A sea urchin gene encodes a polypeptide homologous to epidermal growth factor. Hursh DA, et al. Science, 1987 Sep 18. PMID 3498216
  5. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables biotin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibropellin-1
Names
epidermal growth factor I
epidermal growth factor-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242700.1 → NP_001229629.1  fibropellin-1 precursor

    See identical proteins and their annotated locations for NP_001229629.1

    Status: PROVISIONAL

    Source sequence(s)
    L08692
    UniProtKB/Swiss-Prot
    P10079
    Conserved Domains (3) summary
    cd00054
    Location:366 → 402
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00431
    Location:62 → 173
    CUB; CUB domain
    pfam01382
    Location:940 → 1052
    Avidin; Avidin family

RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Spur_5.0 Primary Assembly

Genomic

  1. NW_022145599.1 Reference Spur_5.0 Primary Assembly

    Range
    33242473..33268883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011685925.2 → XP_011684227.2  fibropellin-1 isoform X1

    UniProtKB/TrEMBL
    A0A7M7HK79
    Conserved Domains (3) summary
    cd00054
    Location:366 → 402
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00431
    Location:62 → 173
    CUB; CUB domain
    pfam01382
    Location:1016 → 1128
    Avidin; Avidin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P10079.2 GenPept UniProtKB/Swiss-Prot:P10079

Gene LinkOut

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