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Pramel32 PRAME like 32 [ Mus musculus (house mouse) ]

Gene ID: 381590, updated on 11-Apr-2024

Summary

Official Symbol
Pramel32provided by MGI
Official Full Name
PRAME like 32provided by MGI
Primary source
MGI:MGI:2140706
See related
Ensembl:ENSMUSG00000038330 AllianceGenome:MGI:2140706
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
4 C4; 4 42.02 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (88545557..88552423, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (88627320..88634186, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L48 pseudogene Neighboring gene interferon alpha 12 Neighboring gene STARR-positive B cell enhancer mm9_chr4:88286951-88287252 Neighboring gene interferon alpha 13 Neighboring gene interferon-alpha 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Clone Names

  • MGC60825

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables ubiquitin-like ligase-substrate adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of Cul2-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198663.3NP_941065.2  PRAME like 32

    See identical proteins and their annotated locations for NP_941065.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and is the protein-coding transcript.
    Source sequence(s)
    AK135883, CA559642
    Consensus CDS
    CCDS51221.1
    UniProtKB/TrEMBL
    Q3UX49, Q7TPT0
    Related
    ENSMUSP00000056691.4, ENSMUST00000053304.10

RNA

  1. NR_027385.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is therefore not thought to encode a protein.
    Source sequence(s)
    AK163216, CJ083078

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    88545557..88552423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)