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CG17249 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38201, updated on 10-May-2024

Summary

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Official Symbol
CG17249provided by FlyBase
Primary source
FLYBASE:FBgn0035249
Locus tag
Dmel_CG17249
See related
AllianceGenome:FB:FBgn0035249
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG17249
Summary
Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in papillary renal cell carcinoma. Orthologous to human PRCC (proline rich mitotic checkpoint control factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG17249 in Genome Data Viewer
Location:
62A9-62A9; 3-0.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1645931..1647464, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1645931..1647464, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Big brother Neighboring gene Coat Protein (coatomer) alpha Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45815 Neighboring gene Brother Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid β Toxicity in the Drosophila Brain. Belfiori-Carrasco LF, et al. Front Aging Neurosci, 2017. PMID 28352227, Free PMC Article
  2. Genetic Dissection of Alzheimer's Disease Using Drosophila Models. Jeon Y, et al. Int J Mol Sci, 2020 Jan 30. PMID 32019113, Free PMC Article
  3. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
  4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17249-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    1645931..1647464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139381.2 → NP_647638.1  uncharacterized protein Dmel_CG17249 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647638.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0B6
    Related
    FBpp0072692
    Conserved Domains (1) summary
    pfam10253
    Location:371 → 472
    PRCC; Mitotic checkpoint regulator, MAD2B-interacting
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W0B6 Q9W0B6

Gene LinkOut

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