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Tmed8 transmembrane p24 trafficking protein 8 [ Mus musculus (house mouse) ]

Gene ID: 382620, updated on 5-Mar-2024

Summary

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Official Symbol
Tmed8provided by MGI
Official Full Name
transmembrane p24 trafficking protein 8provided by MGI
Primary source
MGI:MGI:1923480
See related
Ensembl:ENSMUSG00000034111 AllianceGenome:MGI:1923480
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mem1; Gm1184; 6430595O10Rik
Summary
Is expressed in early conceptus. Orthologous to human TMED8 (transmembrane p24 trafficking protein family member 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 9.6), frontal lobe adult (RPKM 5.6) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
12 D2; 12 41.36 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (87195547..87247264, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (87166242..87200457, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene neuroglobin Neighboring gene protein-O-mannosyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E10770 Neighboring gene STARR-positive B cell enhancer ABC_E10771 Neighboring gene glutathione transferase zeta 1 (maleylacetoacetate isomerase) Neighboring gene predicted gene 6566 Neighboring gene STARR-positive B cell enhancer ABC_E9041 Neighboring gene sterile alpha motif domain containing 15 Neighboring gene NADP+ dependent oxidoreductase domain containing 1 Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene AHA1, activator of heat shock protein ATPase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Murine Bv8 gene maps near a synteny breakpoint of mouse chromosome 6 and human 3p21. Jilek A, et al. Gene, 2000 Oct 3. PMID 11054548
  2. Gata2 maps to mouse chromosome 6. Ciciotte SL, et al. Mamm Genome, 1997 Jan. PMID 9021157
  3. New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. Heyer BS, et al. Mol Reprod Dev, 1997 Jun. PMID 9136115
  4. cDNA cloning and mapping of a novel subtype of glutamine:fructose-6-phosphate amidotransferase (GFAT2) in human and mouse. Oki T, et al. Genomics, 1999 Apr 15. PMID 10198162
  5. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein TMED8
Names
maternal embryonic message 1
transmembrane emp24 domain containing 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033475.3 → NP_001028647.1  protein TMED8

    See identical proteins and their annotated locations for NP_001028647.1

    Status: PROVISIONAL

    Source sequence(s)
    AC132609
    Consensus CDS
    CCDS26072.1
    UniProtKB/Swiss-Prot
    Q3UHI4
    UniProtKB/TrEMBL
    B9EKE7
    Related
    ENSMUSP00000043742.6, ENSMUST00000037418.7
    Conserved Domains (1) summary
    pfam13897
    Location:186 → 325
    GOLD_2; Golgi-dynamics membrane-trafficking

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    87195547..87247264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157514.1 → XP_036013407.1  protein TMED8 isoform X1

    Conserved Domains (1) summary
    pfam13897
    Location:281 → 331
    GOLD_2; Golgi-dynamics membrane-trafficking

  2. XM_030246805.2 → XP_030102665.1  protein TMED8 isoform X3

    Conserved Domains (1) summary
    pfam13897
    Location:76 → 215
    GOLD_2; Golgi-dynamics membrane-trafficking

  3. XM_006516050.5 → XP_006516113.1  protein TMED8 isoform X2

    Conserved Domains (1) summary
    pfam13897
    Location:117 → 256
    GOLD_2; Golgi-dynamics membrane-trafficking
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UHI4.1 GenPept UniProtKB/Swiss-Prot:Q3UHI4

Gene LinkOut

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