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ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate) [ Homo sapiens (human) ]

Gene ID: 386607, updated on 11-Sep-2019

Summary

Official Symbol
ZFP91-CNTFprovided by HGNC
Official Full Name
ZFP91-CNTF readthrough (NMD candidate)provided by HGNC
Primary source
HGNC:HGNC:33441
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZFP91; ZNF757; Zfp-91
Summary
This gene represents a read-through transcript composed of ZFP91 and CNTF sequence. This transcript is thought to be non-coding because it would be subject to nonsense-mediated mRNA decay (NMD). Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Aug 2008]
Expression
Broad expression in testis (RPKM 34.3), bone marrow (RPKM 11.6) and 24 other tissues See more

Genomic context

See ZFP91-CNTF in Genome Data Viewer
Location:
11q12.1
Exon count:
13
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (58579114..58625733)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (58346587..58393206)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369313 Neighboring gene olfactory receptor family 5 subfamily B member 21 Neighboring gene leupaxin Neighboring gene ZFP91 zinc finger protein Neighboring gene ciliary neurotrophic factor Neighboring gene glycine-N-acyltransferase Neighboring gene glycine-N-acyltransferase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough ZFP91-CNTF

Included genes: CNTF, ZFP91

Other Names

  • E3 ubiquitin-protein ligase ZFP91
  • RING-type E3 ubiquitin transferase ZFP91
  • ZFP91-CNTF readthrough (non-protein coding)
  • Zinc finger protein 757
  • zinc finger protein 91 homolog, ciliary neurotrophic factor transcription unit

Clone Names

  • MGC51126

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024091.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AB057443, AP001350, BG721319

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    58579114..58625733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_003104.1: Suppressed sequence

    Description
    NG_003104.1: This RefSeq was permanently suppressed because this region is now thought to be transcribed as a readthrough transcript expressing a fusion protein, rather than co-transcribed.
  2. NM_170768.2: Suppressed sequence

    Description
    NM_170768.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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