U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pdca phosducin a [ Danio rerio (zebrafish) ]

Gene ID: 386613, updated on 27-Mar-2024

Summary

Official Symbol
pdcaprovided by ZNC
Official Full Name
phosducin aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031023-1
See related
Ensembl:ENSDARG00000011886 AllianceGenome:ZFIN:ZDB-GENE-031023-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
PDC; pdc1; pdcr
Summary
Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway and visual perception. Is expressed in eye and retina. Orthologous to human PDC (phosducin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (20882954..20890429, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21224892..21232367, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene proteoglycan 4a Neighboring gene translocated promoter region a, nuclear basket protein Neighboring gene odr-4 GPCR localization factor homolog Neighboring gene prostaglandin-endoperoxide synthase 2a Neighboring gene phospholipase A2, group IVAa (cytosolic, calcium-dependent)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to stimulus IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in photoreceptor inner segment IEA
Inferred from Electronic Annotation
more info
 
is_active_in photoreceptor outer segment IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
phosducin a
Names
PDCb1
phosducin 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291500.1NP_001278429.1  phosducin a

    See identical proteins and their annotated locations for NP_001278429.1

    Status: VALIDATED

    Source sequence(s)
    CU570979
    UniProtKB/TrEMBL
    A0A8M1P6P2, F8W512
    Related
    ENSDARP00000123816.1, ENSDART00000149989.2
    Conserved Domains (1) summary
    cd02987
    Location:9216
    Phd_like_Phd; Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    20882954..20890429 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)