pdcb phosducin b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pdcbprovided by ZNC
Official Full Name: phosducin bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031023-2
See related: Ensembl:ENSDARG00000017634 AllianceGenome:ZFIN:ZDB-GENE-031023-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pdc2; pdcc; zgc:123000
Summary: Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway and visual perception. Orthologous to human PDC (phosducin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (34084331..34090825, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (34181452..34187946, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to stimulus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within visual perception	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in photoreceptor outer segment	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosducin b

Names: PDCb2; phosducin 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025464.2 → NP_001020635.2 phosducin b

Status: VALIDATED

Source sequence(s)

BC076174, BX323056

UniProtKB/TrEMBL

A0A8M1N6T6, Q5RI07, Q6DH10

Related

ENSDARP00000062538.6, ENSDART00000062539.8

Conserved Domains (1) summary

cd02987
Location:14 → 218

Phd_like_Phd; Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes ...