U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

yip7 yippee interacting protein 7 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38680, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
yip7provided by FlyBase
Official Full Name
yippee interacting protein 7provided by FlyBase
Primary source
FLYBASE:FBgn0040060
Locus tag
Dmel_CG6457
See related
AllianceGenome:FB:FBgn0040060
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6457; Dmel\CG6457; mac; MAC; SP116; SPH116; Yip7
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in adult head and embryonic midgut chamber. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
65A3-65A3; 3-16 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6035216..6036175)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6028316..6029275)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene PVR adaptor protein Neighboring gene alpha Karyopherin-4 Neighboring gene long non-coding RNA:CR43952 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes. Bozler J, et al. PLoS Genet, 2017 Oct. PMID 29084214, Free PMC Article
  2. Intellectual disability-associated dBRWD3 regulates gene expression through inhibition of HIRA/YEM-mediated chromatin deposition of histone H3.3. Chen WY, et al. EMBO Rep, 2015 Apr. PMID 25666827, Free PMC Article
  3. Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. Kambris Z, et al. Curr Biol, 2006 Apr 18. PMID 16631589
  4. A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults. Parisi M, et al. Genome Biol, 2004. PMID 15186491, Free PMC Article
  5. Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging. Jiao J, et al. Cell Rep, 2023 Jan 31. PMID 36640359, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
yippee interacting protein 7
Names
CG6457-PA
machete
yip7-PA
NP_523944.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6035216..6036175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079220.2 → NP_523944.1  yippee interacting protein 7 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523944.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JYN3, Q9VRS4
    Related
    FBpp0076746
    Conserved Domains (2) summary
    smart00020
    Location:39 → 264
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:40 → 267
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JYN3 Q7JYN3
Q9NIU1 Q9NIU1
Q9VRS4 Q9VRS4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous