OR52D1 olfactory receptor family 52 subfamily D member 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR52D1provided by HGNC
Official Full Name: olfactory receptor family 52 subfamily D member 1provided by HGNC
Primary source: HGNC:HGNC:15212
See related: Ensembl:ENSG00000181609 AllianceGenome:HGNC:15212
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: OR11-43
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs: mouse all
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Genomic context

Location:: 11p15.4

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	11	NC_000011.10 (5488685..5489749)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	11	NC_060935.1 (5547958..5549022)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	11	NC_000011.9 (5509915..5510979)

Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

REN98375 (e-PCR)
- UniSTS:423172

REN98376 (e-PCR)
- UniSTS:423173

REN98377 (e-PCR)
- UniSTS:423174

REN98378 (e-PCR)
- UniSTS:423175

REN98379 (e-PCR)
- UniSTS:423176

REN98380 (e-PCR)
- UniSTS:423177

REN98381 (e-PCR)
- UniSTS:423178

REN98382 (e-PCR)
- UniSTS:423179

REN98383 (e-PCR)
- UniSTS:423180

REN98384 (e-PCR)
- UniSTS:423181

REN98385 (e-PCR)
- UniSTS:423182

REN98386 (e-PCR)
- UniSTS:423183

REN98387 (e-PCR)
- UniSTS:423184

REN98388 (e-PCR)
- UniSTS:423185

ECD04961 (e-PCR)
- UniSTS:286029

OR52D1__5878 (e-PCR)
- UniSTS:463716

ECD04270 (e-PCR)
- UniSTS:285348

ECD05386 (e-PCR)
- UniSTS:286452

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of smell	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: olfactory receptor 52D1

Names: HOR 5'Beta14; odorant receptor HOR5'beta14; olfactory receptor OR11-43

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.