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tnni2a.2 troponin I type 2a (skeletal, fast), tandem duplicate 2 [ Danio rerio (zebrafish) ]

Gene ID: 394068, updated on 27-Mar-2024

Summary

Official Symbol
tnni2a.2provided by ZNC
Official Full Name
troponin I type 2a (skeletal, fast), tandem duplicate 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-970
See related
Ensembl:ENSDARG00000005841 AllianceGenome:ZFIN:ZDB-GENE-040426-970
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Tnni2; zgc:56294
Summary
Predicted to be involved in cardiac muscle contraction and skeletal muscle contraction. Predicted to be part of troponin complex. Is expressed in cephalic musculature and myotome. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita and distal arthrogryposis type 2B1. Orthologous to human TNNI2 (troponin I2, fast skeletal type). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 25
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (31238606..31248602)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (30661130..30671126)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101884923 Neighboring gene troponin I type 2a (skeletal, fast), tandem duplicate 1 Neighboring gene troponin I type 2a (skeletal, fast), tandem duplicate 3 Neighboring gene troponin I type 2a (skeletal, fast), tandem duplicate 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC56294

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cardiac muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in skeletal muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of troponin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of troponin complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
troponin I type 2a (skeletal, fast), tandem duplicate 2
Names
tropI-1b
troponin I, skeletal, fast 2a, tandem duplicate 2
troponin I, skeletal, fast 2a.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201093.1NP_957387.1  troponin I type 2a (skeletal, fast), tandem duplicate 2

    See identical proteins and their annotated locations for NP_957387.1

    Status: PROVISIONAL

    Source sequence(s)
    BC047857
    UniProtKB/TrEMBL
    Q7ZUR7
    Related
    ENSDARP00000124383.1, ENSDART00000149439.2
    Conserved Domains (1) summary
    pfam00992
    Location:1124
    Troponin; Troponin

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    31238606..31248602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)