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Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B [ Mus musculus (house mouse) ]

Gene ID: 394435, updated on 8-Feb-2024

Summary

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Official Symbol
Ugt1a6bprovided by MGI
Official Full Name
UDP glucuronosyltransferase 1 family, polypeptide A6Bprovided by MGI
Primary source
MGI:MGI:3580629
See related
Ensembl:ENSMUSG00000090145 AllianceGenome:MGI:3580629
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A9'; Ugt1a9
Summary
Predicted to enable enzyme binding activity; glucuronosyltransferase activity; and protein dimerization activity. Predicted to be involved in 4-chlorobiphenyl metabolic process; cellular glucuronidation; and cellular response to glucocorticoid stimulus. Predicted to be located in endoplasmic reticulum. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human UGT1A6 (UDP glucuronosyltransferase family 1 member A6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 328.2), liver adult (RPKM 232.7) and 13 other tissues See more
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Genomic context

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Location:
1 D; 1 44.51 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (88030979..88146720)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (88103257..88218998)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 pseudogene Neighboring gene predicted gene, 38421 Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A9 Neighboring gene STARR-seq mESC enhancer starr_01626 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A8 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A7C Neighboring gene STARR-seq mESC enhancer starr_01627 Neighboring gene STARR-seq mESC enhancer starr_01628 Neighboring gene predicted gene 15372 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6A Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 pseudogene Neighboring gene predicted gene 15371 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A5 Neighboring gene predicted gene 15368 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90112870-90113171 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90113610-90113910 Neighboring gene predicted gene 15376 Neighboring gene STARR-seq mESC enhancer starr_01629 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90118277-90118578 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B3 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A1 Neighboring gene maestro heat-like repeat family member 2A Neighboring gene STARR-positive B cell enhancer mm9_chr1:90185502-90185802 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90186563-90186863 Neighboring gene Holliday junction recognition protein Neighboring gene STARR-positive B cell enhancer mm9_chr1:90195708-90196009 Neighboring gene transient receptor potential cation channel, subfamily M, member 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. Zhang T, et al. Genome Res, 2004 Jan. PMID 14672974, Free PMC Article
  2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC36247

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in 4-chlorobiphenyl metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular glucuronidation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular glucuronidation ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to glucocorticoid stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in xenobiotic metabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
UDP glucuronosyltransferase 1 family, polypeptide A6B
Names
UDP glycosyltransferase 1 family polypeptide A9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201410.3 → NP_958812.3  UDP glucuronosyltransferase 1 family, polypeptide A6B precursor

    Status: VALIDATED

    Source sequence(s)
    AC087780, AC087801
    Consensus CDS
    CCDS48313.1
    UniProtKB/TrEMBL
    K9J7B2, Q8R0P3
    Related
    ENSMUSP00000108763.2, ENSMUST00000113138.8
    Conserved Domains (2) summary
    PHA03392
    Location:15 → 503
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:27 → 522
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    88030979..88146720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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