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Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 [ Mus musculus (house mouse) ]

Gene ID: 394436, updated on 23-Jun-2021

Summary

Official Symbol
Ugt1a1provided by MGI
Official Full Name
UDP glucuronosyltransferase 1 family, polypeptide A1provided by MGI
Primary source
MGI:MGI:98898
See related
Ensembl:ENSMUSG00000089960
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gnt; Gnt1; UgtBr; UGT1A0; Udpgt-; UgtBr1; UGT1A01; Udpgt-1a; UDPGT 1-1
Expression
Biased expression in kidney adult (RPKM 233.7), liver adult (RPKM 207.2) and 9 other tissues See more
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Genomic context

See Ugt1a1 in Genome Data Viewer
Location:
1 D; 1 44.55 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (88139681..88147724)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (88211959..88220002)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (90108534..90116577)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A9 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A8 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A7C Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6B Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6A Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A5 Neighboring gene predicted gene 15376 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B3 Neighboring gene maestro heat-like repeat family member 2A Neighboring gene Holliday junction recognition protein Neighboring gene transient receptor potential cation channel, subfamily M, member 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables retinoic acid binding ISO
Inferred from Sequence Orthology
more info
 
enables steroid binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biphenyl catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular glucuronidation ISO
Inferred from Sequence Orthology
more info
 
involved_in estrogen metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in flavone metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in flavonoid glucuronidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in flavonoid glucuronidation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cellular glucuronidation ISO
Inferred from Sequence Orthology
more info
 
involved_in response to organic substance ISO
Inferred from Sequence Orthology
more info
 
involved_in xenobiotic glucuronidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in xenobiotic glucuronidation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of cytochrome complex ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
part_of endoplasmic reticulum chaperone complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
UDP-glucuronosyltransferase 1A1
Names
UDP-glucuronosyltransferase 1 family, member 1
UDP-glucuronosyltransferase 1-1
UDPGT
UGT1*1
UGT1-01
UGT1.1
NP_964007.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201645.2NP_964007.2  UDP-glucuronosyltransferase 1A1 precursor

    See identical proteins and their annotated locations for NP_964007.2

    Status: VALIDATED

    Source sequence(s)
    AA674349, AC087780, AI097692
    Consensus CDS
    CCDS15143.1
    UniProtKB/Swiss-Prot
    Q63886
    Related
    ENSMUSP00000072803.7, ENSMUST00000073049.7
    Conserved Domains (2) summary
    PHA03392
    Location:20507
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:30526
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    88139681..88147724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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