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CLU clusterin [ Gallus gallus (chicken) ]

Gene ID: 395722, updated on 3-Oct-2021

Summary

Official Symbol
CLUprovided by CGNC
Official Full Name
clusterinprovided by CGNC
Primary source
CGNC:12427
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
SP-40
Summary
This gene encodes a protein that is similar to the human clusterin protein, a secreted chaperone that can also be found in the cell cytosol under certain stress conditions. The human protein has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. [provided by RefSeq, May 2011]
Orthologs
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Genomic context

See CLU in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (105000140..105007013)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 3 NC_052575.1 (104765561..104770657)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 3 NC_006090.4 (105645313..105652240)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 25 Neighboring gene scavenger receptor class A member 3 Neighboring gene uncharacterized LOC121110417 Neighboring gene solute carrier family 35 member F6 Neighboring gene potassium two pore domain channel subfamily K member 3

Genomic regions, transcripts, and products

General gene information

Homology

General protein information

Preferred Names
clusterin
Names
apolipoprotein J)
clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
sulfated glycoprotein 2
testosterone-repressed prostate message 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396177.1NP_001383106.1  clusterin precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070
  2. NM_001396178.1NP_001383107.1  clusterin precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070
  3. NM_204900.2NP_990231.2  clusterin precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    105000140..105007013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040696819.1XP_040552753.1  clusterin isoform X1

    Conserved Domains (2) summary
    smart00030
    Location:40236
    CLb; CLUSTERIN Beta chain
    smart00035
    Location:253463
    CLa; CLUSTERIN alpha chain
  2. XM_040696820.1XP_040552754.1  clusterin isoform X2

    Conserved Domains (2) summary
    smart00030
    Location:19215
    CLb; CLUSTERIN Beta chain
    smart00035
    Location:232442
    CLa; CLUSTERIN alpha chain
  3. XM_040696821.1XP_040552755.1  clusterin isoform X2

    Conserved Domains (2) summary
    smart00030
    Location:19215
    CLb; CLUSTERIN Beta chain
    smart00035
    Location:232442
    CLa; CLUSTERIN alpha chain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    104765561..104770657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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