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AXIN1 axin 1 [ Gallus gallus (chicken) ]

Gene ID: 395786, updated on 6-Nov-2021

Summary

Symbol
AXIN1provided by CGNC
Full Name
axin 1provided by CGNC
Primary source
CGNC:49477
See related
Ensembl:ENSGALG00000029402
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
AXIN; axin-1; AXIN1-RGS
Orthologs
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Genomic context

See AXIN1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (12159826..12235940)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 14 NC_052586.1 (12162807..12231545)
104 previous assembly GRCg6a (GCF_000002315.5) 14 NC_006101.5 (12551047..12629125)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 14 NC_006101.4 (12212115..12282361)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 8A Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene uncharacterized LOC121106767 Neighboring gene uncharacterized LOC121106768 Neighboring gene protein disulfide isomerase family A member 2 Neighboring gene Rho GDP dissociation inhibitor gamma

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables beta-catenin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of JNK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasmic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
axin-1
Names
axis inhibition protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204944.3NP_990275.2  axin-1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000257
    Related
    ENSGALP00000047150.1, ENSGALT00000055308.3
    Conserved Domains (4) summary
    cd08707
    Location:89209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:1180
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761838
    DIX; DIX domain
    pfam08833
    Location:467503
    Axin_b-cat_bind; Axin beta-catenin binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12159826..12235940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025155050.2XP_025010818.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:1180
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761838
    DIX; DIX domain
    pfam08833
    Location:467503
    Axin_b-cat_bind; Axin beta-catenin binding domain
  2. XM_015294136.3XP_015149622.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395
    Conserved Domains (4) summary
    cd08707
    Location:89209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:1180
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761838
    DIX; DIX domain
    pfam08833
    Location:467503
    Axin_b-cat_bind; Axin beta-catenin binding domain
  3. XM_040647318.1XP_040503252.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:1180
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761838
    DIX; DIX domain
    pfam08833
    Location:467503
    Axin_b-cat_bind; Axin beta-catenin binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12162807..12231545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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