Format

Send to:

Choose Destination

ZEB1 zinc finger E-box binding homeobox 1 [ Gallus gallus (chicken) ]

Gene ID: 396029, updated on 6-Nov-2021

Summary

Official Symbol
ZEB1provided by CGNC
Official Full Name
zinc finger E-box binding homeobox 1provided by CGNC
Primary source
CGNC:5487
See related
Ensembl:ENSGALG00000007260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
TCF8
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZEB1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (14305732..14411619, complement)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 2 NC_052574.1 (14332512..14437866, complement)
104 previous assembly GRCg6a (GCF_000002315.5) 2 NC_006089.5 (14388427..14494371, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 2 NC_006089.4 (14376486..14497714, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 5B Neighboring gene Rho GTPase activating protein 12 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC101750758 Neighboring gene uncharacterized LOC107052596

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables E-box binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
zinc finger E-box-binding homeobox 1
Names
TCF-8
delta EF1
delta-crystallin enhancer-binding factor
deltaEF1
transcription factor 8 (represses interleukin 2 expression)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205131.2NP_990462.2  zinc finger E-box-binding homeobox 1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000036
    Related
    ENSGALP00000011738.3, ENSGALT00000011752.4
    Conserved Domains (5) summary
    COG5271
    Location:28197
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    sd00017
    Location:906926
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:240262
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:946971
    zf-H2C2_2; Zinc-finger double domain
    cl00084
    Location:593629
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14305732..14411619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040676250.1XP_040532184.1  zinc finger E-box-binding homeobox 1 isoform X2

    Conserved Domains (3) summary
    smart00355
    Location:2244
    ZnF_C2H2; zinc finger
    smart00389
    Location:375411
    HOX; Homeodomain
    sd00017
    Location:688708
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_015281304.3XP_015136790.2  zinc finger E-box-binding homeobox 1 isoform X1

    Conserved Domains (3) summary
    smart00355
    Location:241263
    ZnF_C2H2; zinc finger
    smart00389
    Location:594630
    HOX; Homeodomain
    sd00017
    Location:907927
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_040676245.1XP_040532179.1  zinc finger E-box-binding homeobox 1 isoform X2

    Conserved Domains (3) summary
    smart00355
    Location:2244
    ZnF_C2H2; zinc finger
    smart00389
    Location:375411
    HOX; Homeodomain
    sd00017
    Location:688708
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_040676238.1XP_040532172.1  zinc finger E-box-binding homeobox 1 isoform X2

    Conserved Domains (3) summary
    smart00355
    Location:2244
    ZnF_C2H2; zinc finger
    smart00389
    Location:375411
    HOX; Homeodomain
    sd00017
    Location:688708
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    14332512..14437866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center