GOT1 glutamic-oxaloacetic transaminase 1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: GOT1provided by CGNC
Official Full Name: glutamic-oxaloacetic transaminase 1provided by CGNC
Primary source: CGNC:5645
See related: Ensembl:ENSGALG00010018323
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: cCAT; cAspAT
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	6	NC_052537.1 (22932811..22936402)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	6	NC_052578.1 (22824084..22827666)

Chromosome 6 - NC_052537.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables L-aspartate:2-oxoglutarate aminotransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in aspartate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: aspartate aminotransferase, cytoplasmic

Names: cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; glutamate oxaloacetate transaminase 1; glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1); transaminase A

NP_990652.1

EC 2.6.1.1

EC 2.6.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205321.2 → NP_990652.1 aspartate aminotransferase, cytoplasmic

See identical proteins and their annotated locations for NP_990652.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000232

UniProtKB/Swiss-Prot

P00504

Related

ENSGALP00010026301.1, ENSGALT00010044218.1

Conserved Domains (2) summary

pfam00155
Location:32 → 404

Aminotran_1_2; Aminotransferase class I and II

cl18945
Location:1 → 412

AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...