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MYH10 myosin, heavy chain 10, non-muscle [ Gallus gallus (chicken) ]

Gene ID: 396465, updated on 3-Apr-2024

Summary

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Official Symbol
MYH10provided by CGNC
Official Full Name
myosin, heavy chain 10, non-muscleprovided by CGNC
Primary source
CGNC:49817
See related
Ensembl:ENSGALG00010029349
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
myosin; myosin-10; non-muscle
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
44
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (2345560..2438788, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (1915014..2008104, complement)

Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 222 Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene uncharacterized LOC101749287 Neighboring gene uncharacterized LOC107054732 Neighboring gene coiled-coil domain containing 42

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental relationship of myosin binding proteins (myomesin, connectin and C-protein) to myosin in chicken somites as studied by immunofluorescence microscopy. Yang YG, et al. Cell Struct Funct, 2000 Jun. PMID 10984101
  2. Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. Cloning of the cDNA encoding the myosin heavy chain-B isoform of vertebrate nonmuscle myosin. Takahashi M, et al. J Biol Chem, 1992 Sep 5. PMID 1355479
  3. Two distinct nonmuscle myosin-heavy-chain mRNAs are differentially expressed in various chicken tissues. Identification of a novel gene family of vertebrate non-sarcomeric myosin heavy chains. Katsuragawa Y, et al. Eur J Biochem, 1989 Oct 1. PMID 2806244

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin-10
Names
heavy polypeptide 10
myosin, heavy polypeptide 10, non-muscle
nonmuscle myosin II heavy chain-B
nonmuscle myosin heavy chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205474.2 → NP_990805.1  myosin-10

    See identical proteins and their annotated locations for NP_990805.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000315
    UniProtKB/TrEMBL
    A0A8V1AJQ0, Q789A4
    Related
    ENSGALP00010043669.1, ENSGALT00010070978.1
    Conserved Domains (10) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    cd16269
    Location:1624 → 1635
    GBP_C; coiled coil [structural motif]
    cl19219
    Location:1075 → 1164
    DUF342; Protein of unknown function (DUF342)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl20817
    Location:1535 → 1644
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl24005
    Location:1804 → 1898
    DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2345560..2438788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040649469.2 → XP_040505403.1  myosin-10 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AHP5, F1NGG0, Q789A6
    Conserved Domains (3) summary
    cd14920
    Location:99 → 771
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam01576
    Location:848 → 1928
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:33 → 68
    Myosin_N; Myosin N-terminal SH3-like domain

  2. XM_015295125.4 → XP_015150611.1  myosin-10 isoform X2

    UniProtKB/TrEMBL
    A0A8V1ANB1, Q02015
    Related
    ENSGALP00010043670.1, ENSGALT00010070979.1
    Conserved Domains (3) summary
    cd14920
    Location:99 → 792
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam01576
    Location:869 → 1949
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:33 → 68
    Myosin_N; Myosin N-terminal SH3-like domain

  3. XM_046901984.1 → XP_046757940.1  myosin-10 isoform X3

    UniProtKB/TrEMBL
    Q789A5
    Related
    ENSGALP00010043671.1, ENSGALT00010070980.1

  4. XM_015295124.3 → XP_015150610.1  myosin-10 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AJQ0, Q789A4
    Conserved Domains (10) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    cd16269
    Location:1624 → 1635
    GBP_C; coiled coil [structural motif]
    cl19219
    Location:1075 → 1164
    DUF342; Protein of unknown function (DUF342)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl20817
    Location:1535 → 1644
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl24005
    Location:1804 → 1898
    DUF2570; Protein of unknown function (DUF2570)

  5. XM_040649470.2 → XP_040505404.1  myosin-10 isoform X5

    UniProtKB/TrEMBL
    A0A8V1ANB1
    Conserved Domains (4) summary
    COG1196
    Location:829 → 1669
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5022
    Location:1 → 1159
    COG5022; Myosin heavy chain [General function prediction only]
    cl30717
    Location:1600 → 1766
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    cl22853
    Location:2 → 582
    Motor_domain; Myosin and Kinesin motor domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1915014..2008104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046929274.1 → XP_046785230.1  myosin-10 isoform X4

    UniProtKB/TrEMBL
    F1NGG0, Q789A6

  2. XM_046929271.1 → XP_046785227.1  myosin-10 isoform X2

    UniProtKB/TrEMBL
    Q02015

  3. XM_046929272.1 → XP_046785228.1  myosin-10 isoform X3

    UniProtKB/TrEMBL
    Q789A5

  4. XM_046929270.1 → XP_046785226.1  myosin-10 isoform X1

    UniProtKB/TrEMBL
    Q789A4

  5. XM_046929275.1 → XP_046785231.1  myosin-10 isoform X5

Nucleotide Protein
Heading Accession and Version

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