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GOT2 glutamic-oxaloacetic transaminase 2 [ Gallus gallus (chicken) ]

Gene ID: 396533, updated on 14-Jan-2019

Summary

Symbol
GOT2provided by CGNC
Full Name
glutamic-oxaloacetic transaminase 2provided by CGNC
Primary source
CGNC:1656
See related
Ensembl:ENSGALG00000002321
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See GOT2 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
11
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 11 NC_006098.5 (1475178..1485088, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 11 NC_006098.4 (1534704..1544641, complement)

Chromosome 11 - NC_006098.5Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex subunit 1 Neighboring gene small nucleolar RNA SNORA50 Neighboring gene solute carrier family 38 member 7 Neighboring gene calbindin 2 Neighboring gene purine nucleoside phosphorylase

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
L-aspartate:2-oxoglutarate aminotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-aspartate:2-oxoglutarate aminotransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
L-aspartate:2-oxoglutarate aminotransferase activity TAS
Traceable Author Statement
more info
 
kynurenine-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
2-oxoglutarate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
L-kynurenine metabolic process IEA
Inferred from Electronic Annotation
more info
 
aspartate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aspartate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
cellular amino acid metabolic process TAS
Traceable Author Statement
more info
 
gluconeogenesis TAS
Traceable Author Statement
more info
 
glutamate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
mitochondrial matrix TAS
Traceable Author Statement
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
aspartate aminotransferase, mitochondrial
Names
glutamate oxaloacetate transaminase 2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
kynurenine aminotransferase 4
kynurenine aminotransferase IV
kynurenine--oxoglutarate transaminase 4
kynurenine--oxoglutarate transaminase IV
mAspAT
transaminase A
NP_990854.1
XP_015134609.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205523.1NP_990854.1  aspartate aminotransferase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_990854.1

    Status: PROVISIONAL

    Source sequence(s)
    M12105
    UniProtKB/Swiss-Prot
    P00508
    Related
    ENSGALP00000003646.3, ENSGALT00000003653.6
    Conserved Domains (2) summary
    PLN02397
    Location:25423
    PLN02397; aspartate transaminase
    pfam00155
    Location:50418
    Aminotran_1_2; Aminotransferase class I and II

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006098.5 Reference GRCg6a Primary Assembly

    Range
    1475178..1485088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279123.2XP_015134609.1  aspartate aminotransferase, mitochondrial isoform X1

    Conserved Domains (2) summary
    pfam00155
    Location:50337
    Aminotran_1_2; Aminotransferase class I and II
    cl18945
    Location:25337
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
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