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CELA1 chymotrypsin like elastase 1 [ Sus scrofa (pig) ]

Gene ID: 396766, updated on 11-Jun-2019

Summary

Gene symbol
CELA1
Gene description
chymotrypsin like elastase 1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
Also known as
ELA1; ELS1; Elastase-1
Expression
Biased expression in ovary (RPKM 10.0) and spleen (RPKM 2.4) See more
Orthologs

Genomic context

See CELA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018085018.1 (62822..89758)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (17250142..17279128, complement)

NW_018085018.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 6 Neighboring gene bridging integrator 2 Neighboring gene small cell adhesion glycoprotein Neighboring gene DAZ associated protein 2

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
elastin catabolic process IEA
Inferred from Electronic Annotation
more info
 
exocrine pancreas development IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
multicellular organism growth IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
pancreas morphogenesis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
post-embryonic development IEA
Inferred from Electronic Annotation
more info
 
regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
tissue remodeling IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
chymotrypsin-like elastase family member 1
Names
chymotrypsin like elastase family member 1
pancreatic elastase I
NP_998988.1
XP_005655631.2
XP_020937363.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213823.1NP_998988.1  chymotrypsin-like elastase family member 1 preproprotein

    See identical proteins and their annotated locations for NP_998988.1

    Status: VALIDATED

    Source sequence(s)
    D00160
    UniProtKB/Swiss-Prot
    P00772
    Conserved Domains (2) summary
    smart00020
    Location:26259
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:27262
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NW_018085018.1 Reference Sscrofa11.1 Primary Assembly

    Range
    62822..89758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005655574.3XP_005655631.2  chymotrypsin-like elastase family member 1 isoform X1

    Conserved Domains (1) summary
    cd00190
    Location:67302
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
  2. XM_021081704.1XP_020937363.1  chymotrypsin-like elastase family member 1 isoform X2

    Conserved Domains (1) summary
    cd00190
    Location:27262
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
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