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FBP1 fructose-bisphosphatase 1 [ Sus scrofa (pig) ]

Gene ID: 397038, updated on 19-Mar-2019

Summary

Gene symbol
FBP1
Gene description
fructose-bisphosphatase 1
See related
Ensembl:ENSSSCG00000031174
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
Also known as
FBP
Expression
Biased expression in kidney (RPKM 818.9), liver (RPKM 579.0) and 1 other tissue See more
Orthologs

Genomic context

See FBP1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 10 NC_010452.4 (27588609..27622225)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 10 NC_010452.3 (31712560..31829432)

Chromosome 10 - NC_010452.4Genomic Context describing neighboring genes Neighboring gene microRNA 23b Neighboring gene aminopeptidase O (putative) Neighboring gene uncharacterized LOC102158497 Neighboring gene fructose-bisphosphatase 2 Neighboring gene cathepsin L

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
AMP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
RNA polymerase II transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
fructose 1,6-bisphosphate 1-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
monosaccharide binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
cellular response to drug ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to magnesium ion ISS
Inferred from Sequence or Structural Similarity
more info
 
dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
fructose 6-phosphate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 
gluconeogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of Ras protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of cell growth ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of glycolytic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
protein homotetramerization ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of gluconeogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fructose-1,6-bisphosphatase 1
Names
D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
FBPase 1
fructose 1,6-bisphosphatase
liver FBPase
NP_999144.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213979.1NP_999144.1  fructose-1,6-bisphosphatase 1

    See identical proteins and their annotated locations for NP_999144.1

    Status: PROVISIONAL

    Source sequence(s)
    M86347
    UniProtKB/Swiss-Prot
    P00636
    Related
    ENSSSCP00000049752.1, ENSSSCT00000065852.1
    Conserved Domains (1) summary
    cd00354
    Location:18332
    FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010452.4 Reference Sscrofa11.1 Primary Assembly

    Range
    27588609..27622225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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