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FTCD formimidoyltransferase cyclodeaminase [ Sus scrofa (pig) ]

Gene ID: 397517, updated on 5-Mar-2024

Summary

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Gene symbol
FTCD
Gene description
formimidoyltransferase cyclodeaminase
See related
Ensembl:ENSSSCG00000027926
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in liver (RPKM 156.8), kidney (RPKM 87.5) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018085356.1 (580183..594555)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (218617763..218632226, complement)

NW_018085356.1Genomic Context describing neighboring genes Neighboring gene lanosterol synthase Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene collagen type VI alpha 2 chain Neighboring gene uncharacterized LOC110259167

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. The nucleotide sequence of porcine formiminotransferase cyclodeaminase. Expression and purification from Escherichia coli. Murley LL, et al. J Biol Chem, 1993 Oct 25. PMID 7901203
  2. An improved procedure for the purification of formiminotransferase-cyclodeaminase from pig liver. Kinetics of the transferase activity with tetrahydropteroylpolyglutamates. Findlay WA, et al. Biochim Biophys Acta, 1989 Nov 9. PMID 2572277
  3. The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme. Kohls D, et al. Structure, 2000 Jan 15. PMID 10673422

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables folic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
formimidoyltransferase-cyclodeaminase
Names
formiminotransferase cyclodeaminase
NP_999440.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214275.1 → NP_999440.1  formimidoyltransferase-cyclodeaminase

    See identical proteins and their annotated locations for NP_999440.1

    Status: PROVISIONAL

    Source sequence(s)
    L16507
    UniProtKB/Swiss-Prot
    P53603
    UniProtKB/TrEMBL
    A0A480RMM6, A0A4X1T4Z3
    Related
    ENSSSCP00000022108.3, ENSSSCT00000026888.3
    Conserved Domains (4) summary
    TIGR02024
    Location:1 → 328
    FtcD; glutamate formiminotransferase
    pfam02971
    Location:181 → 324
    FTCD; Formiminotransferase domain
    pfam04961
    Location:339 → 519
    FTCD_C; Formiminotransferase-cyclodeaminase
    pfam07837
    Location:7 → 179
    FTCD_N; Formiminotransferase domain, N-terminal subdomain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NW_018085356.1 Reference Sscrofa11.1 Primary Assembly

    Range
    580183..594555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53603.1 GenPept UniProtKB/Swiss-Prot:P53603

Gene LinkOut

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